![IJMS | Free Full-Text | A Mechanism of O-Demethylation of Aristolochic Acid I by Cytochromes P450 and Their Contributions to This Reaction in Human and Rat Livers: Experimental and Theoretical Approaches IJMS | Free Full-Text | A Mechanism of O-Demethylation of Aristolochic Acid I by Cytochromes P450 and Their Contributions to This Reaction in Human and Rat Livers: Experimental and Theoretical Approaches](https://www.mdpi.com/ijms/ijms-16-26047/article_deploy/html/images/ijms-16-26047-g004.png)
IJMS | Free Full-Text | A Mechanism of O-Demethylation of Aristolochic Acid I by Cytochromes P450 and Their Contributions to This Reaction in Human and Rat Livers: Experimental and Theoretical Approaches
![WO2011124190A2 - Method of producing 4-(2-(substituted)-1-(1-hydroxycyclohexyl)ethyl)phenols by o- demethylation of their methylethers by means of inodorous aromatic thiols - Google Patents WO2011124190A2 - Method of producing 4-(2-(substituted)-1-(1-hydroxycyclohexyl)ethyl)phenols by o- demethylation of their methylethers by means of inodorous aromatic thiols - Google Patents](https://patentimages.storage.googleapis.com/73/d6/b9/4e67b79f876326/imgf000005_0001.png)
WO2011124190A2 - Method of producing 4-(2-(substituted)-1-(1-hydroxycyclohexyl)ethyl)phenols by o- demethylation of their methylethers by means of inodorous aromatic thiols - Google Patents
O-Demethylation of IX by human P450 enzymes leads to the formation of... | Download Scientific Diagram
![C-demethylation and 1, 2-amino shift in (E)-2-(1-(3-aminophenyl) ethylidene)hydrazinecarboxamide to (E)-2-(2-aminobenzylidene)hydrazinecarboxamide and their applications | Scientific Reports C-demethylation and 1, 2-amino shift in (E)-2-(1-(3-aminophenyl) ethylidene)hydrazinecarboxamide to (E)-2-(2-aminobenzylidene)hydrazinecarboxamide and their applications | Scientific Reports](https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fs41598-020-79027-1/MediaObjects/41598_2020_79027_Sch1_HTML.png)
C-demethylation and 1, 2-amino shift in (E)-2-(1-(3-aminophenyl) ethylidene)hydrazinecarboxamide to (E)-2-(2-aminobenzylidene)hydrazinecarboxamide and their applications | Scientific Reports
![IJMS | Free Full-Text | A Mechanism of O-Demethylation of Aristolochic Acid I by Cytochromes P450 and Their Contributions to This Reaction in Human and Rat Livers: Experimental and Theoretical Approaches IJMS | Free Full-Text | A Mechanism of O-Demethylation of Aristolochic Acid I by Cytochromes P450 and Their Contributions to This Reaction in Human and Rat Livers: Experimental and Theoretical Approaches](https://www.mdpi.com/ijms/ijms-16-26047/article_deploy/html/images/ijms-16-26047-g001.png)
IJMS | Free Full-Text | A Mechanism of O-Demethylation of Aristolochic Acid I by Cytochromes P450 and Their Contributions to This Reaction in Human and Rat Livers: Experimental and Theoretical Approaches
![Redundancy in Aromatic O-Demethylation and Ring-Opening Reactions in Novosphingobium aromaticivorans and Their Impact in the Metabolism of Plant-Derived Phenolics | Applied and Environmental Microbiology Redundancy in Aromatic O-Demethylation and Ring-Opening Reactions in Novosphingobium aromaticivorans and Their Impact in the Metabolism of Plant-Derived Phenolics | Applied and Environmental Microbiology](https://journals.asm.org/cms/10.1128/AEM.02794-20/asset/7d0d1178-eaa0-4472-a874-b9c03b87f789/assets/images/large/aem.02794-20_f011.jpg)
Redundancy in Aromatic O-Demethylation and Ring-Opening Reactions in Novosphingobium aromaticivorans and Their Impact in the Metabolism of Plant-Derived Phenolics | Applied and Environmental Microbiology
![Valorization of lignin components into gallate by integrated biological hydroxylation, O-demethylation, and aryl side-chain oxidation | Science Advances Valorization of lignin components into gallate by integrated biological hydroxylation, O-demethylation, and aryl side-chain oxidation | Science Advances](https://www.science.org/cms/10.1126/sciadv.abg4585/asset/98b21462-19cc-48bb-af54-a0f01948836c/assets/images/large/sciadv.abg4585-f1.jpg)
Valorization of lignin components into gallate by integrated biological hydroxylation, O-demethylation, and aryl side-chain oxidation | Science Advances
Efficient O-demethylation of lignin monoaromatics using the peroxygenase activity of cytochrome P450 enzymes - Chemical Communications (RSC Publishing)
![PDF] A Mechanism of O-Demethylation of Aristolochic Acid I by Cytochromes P450 and Their Contributions to This Reaction in Human and Rat Livers: Experimental and Theoretical Approaches | Semantic Scholar PDF] A Mechanism of O-Demethylation of Aristolochic Acid I by Cytochromes P450 and Their Contributions to This Reaction in Human and Rat Livers: Experimental and Theoretical Approaches | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/93855323885a33ea512281baecaff6d04ab03e2a/2-Figure1-1.png)
PDF] A Mechanism of O-Demethylation of Aristolochic Acid I by Cytochromes P450 and Their Contributions to This Reaction in Human and Rat Livers: Experimental and Theoretical Approaches | Semantic Scholar
Regioselective aromatic O-demethylation with an artificial P450BM3 peroxygenase system - Catalysis Science & Technology (RSC Publishing)
![Structure of aryl O-demethylase offers molecular insight into a catalytic tyrosine-dependent mechanism | PNAS Structure of aryl O-demethylase offers molecular insight into a catalytic tyrosine-dependent mechanism | PNAS](https://www.pnas.org/cms/10.1073/pnas.1619263114/asset/7f2d381f-ab8a-48c3-8158-3bcabb9f96a8/assets/graphic/pnas.1619263114fig01.jpeg)
Structure of aryl O-demethylase offers molecular insight into a catalytic tyrosine-dependent mechanism | PNAS
![Design and Development of Pd‐Catalyzed Aerobic N‐Demethylation Strategies for the Synthesis of Noroxymorphone in Continuous Flow Mode - Gutmann - 2017 - European Journal of Organic Chemistry - Wiley Online Library Design and Development of Pd‐Catalyzed Aerobic N‐Demethylation Strategies for the Synthesis of Noroxymorphone in Continuous Flow Mode - Gutmann - 2017 - European Journal of Organic Chemistry - Wiley Online Library](https://chemistry-europe.onlinelibrary.wiley.com/cms/asset/4d2f68d7-25d6-4128-afda-c9395546b96d/ejoc201601453-toc-0001-m.jpg)
Design and Development of Pd‐Catalyzed Aerobic N‐Demethylation Strategies for the Synthesis of Noroxymorphone in Continuous Flow Mode - Gutmann - 2017 - European Journal of Organic Chemistry - Wiley Online Library
![PDF] Anaerobic O-demethylation in acetobacterium dehalogenans : interaction mediated by O-demethylase components | Semantic Scholar PDF] Anaerobic O-demethylation in acetobacterium dehalogenans : interaction mediated by O-demethylase components | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/3f973fd89910db3b78baeec7465f3257b860b0b8/13-Figure1.3-1.png)
PDF] Anaerobic O-demethylation in acetobacterium dehalogenans : interaction mediated by O-demethylase components | Semantic Scholar
![Regioselective aromatic O -demethylation with an artificial P450BM3 peroxygenase system - Catalysis Science & Technology (RSC Publishing) DOI:10.1039/D0CY00241K Regioselective aromatic O -demethylation with an artificial P450BM3 peroxygenase system - Catalysis Science & Technology (RSC Publishing) DOI:10.1039/D0CY00241K](https://pubs.rsc.org/image/article/2020/CY/d0cy00241k/d0cy00241k-s1_hi-res.gif)
Regioselective aromatic O -demethylation with an artificial P450BM3 peroxygenase system - Catalysis Science & Technology (RSC Publishing) DOI:10.1039/D0CY00241K
![Molecules | Free Full-Text | Protein Engineering of an Artificial P450BM3 Peroxygenase System Enables Highly Selective O-Demethylation of Lignin Monomers Molecules | Free Full-Text | Protein Engineering of an Artificial P450BM3 Peroxygenase System Enables Highly Selective O-Demethylation of Lignin Monomers](https://www.mdpi.com/molecules/molecules-27-03120/article_deploy/html/images/molecules-27-03120-g001.png)
Molecules | Free Full-Text | Protein Engineering of an Artificial P450BM3 Peroxygenase System Enables Highly Selective O-Demethylation of Lignin Monomers
![A promiscuous cytochrome P450 aromatic O-demethylase for lignin bioconversion | Nature Communications A promiscuous cytochrome P450 aromatic O-demethylase for lignin bioconversion | Nature Communications](https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fs41467-018-04878-2/MediaObjects/41467_2018_4878_Fig6_HTML.jpg)
A promiscuous cytochrome P450 aromatic O-demethylase for lignin bioconversion | Nature Communications
![CYP4F Enzymes Are the Major Enzymes in Human Liver Microsomes That Catalyze the O-Demethylation of the Antiparasitic Prodrug DB289 [2,5-Bis(4-amidinophenyl)furan-bis-O-methylamidoxime] | Drug Metabolism & Disposition CYP4F Enzymes Are the Major Enzymes in Human Liver Microsomes That Catalyze the O-Demethylation of the Antiparasitic Prodrug DB289 [2,5-Bis(4-amidinophenyl)furan-bis-O-methylamidoxime] | Drug Metabolism & Disposition](https://dmd.aspetjournals.org/content/dmd/34/12/1985/F1.large.jpg)